LV Edge System

Integrating stable cell lines and software design tools to routinely achieve lentiviral titers over 1E8 TU/mL for therapeutic transgenes

OVERVIEW

Lower your lentivirus production costs

Applications

The LV Edge System consists of three components: (1) A clonal, suspension-adapted engineered cell line with stably-integrated lentiviral genes under inducible control, (2) Model-guided DNA design to optimize expression of your Gene of Interest (GOI) - powered by Kernel, Asimov's computer-aided design (CAD) software, and (3) Robust, ready-to-transfer processes and protocols across multiple scales.

Choose from a semi-stable packaging system or a fully-stable producer system.

Asimov L V Edge System Component Diagram
Partnering with Asimov

How to work with us

We provide tools for you to develop a cell line

We will ship the software, cells, and genes you need to design your cell line in-house.

We develop a cell line for you

Using our platform, we will design a custom cell line specifically for your needs and ship it to you.

Cell line delivery

We provide tools for you to develop a cell line

We will ship the software, cells, and genes you need to design your cell line in-house.

Plasmid design interface

You design DNA

You use our software to design and optimize genetic constructs using best-in-class parts and models.

Ship DNA icon

We build DNA

We will ship the software, cells, and genes you need to design your cell line in-house.

DNA transfection into cells

You transfect cells

You transfect and generate stable cell lines and use our software for data analysis.

Cell line selection

You request producer cells

You request a producer cell line for a biologic or gene therapy.

DNA design and development interface

We do cell line development

We do cell line development and process development at our site.

Communication bubbles

We share progress

We share progress and data with you using 
our software.

Cell line delivery

We ship you producer cell banks

We ship you clonal cell banks and transfer the process to your site.

We provide tools for you to develop a cell line

We will ship the software, cells, and genes you need to design your cell line in-house.

We develop a cell line for you

Using our platform, we will design a custom cell line specifically for your needs and ship it to you.

Ship CHO cells icon

We provide tools for you to develop a cell line

We will ship the software, cells, and genes you need to design your cell line in-house.

DNA design icon

You design DNA

You use our software to design and optimize genetic constructs using best-in-class parts and models.

Ship DNA icon

We build DNA

We will ship the software, cells, and genes you need to design your cell line in-house.

CLD performance icon

You transfect cells

You transfect and generate stable cell lines and use our software for data analysis.

CHO cell line request icon

You request producer cells

You request a producer cell line for a biologic or gene therapy.

CLD process development icon

We do cell line development

We do cell line development and process development at our site.

CLD process development icon

We share progress

We share progress and data with you using 
our software.

Up to date icon

We ship you producer cell banks

We ship you clonal cell banks and transfer theprocess to your site.

We develop a cell line for you

Using our platform, we will design a custom cell line specifically for your needs and ship it to you.

Ship CHO cells icon

We provide tools for you to develop a cell line

We will ship the software, cells, and genes you need to design your cell line in-house.

DNA design icon

You design DNA

You use our software to design and optimize genetic constructs using best-in-class parts and models.

Ship DNA icon

We build DNA

We will ship the software, cells, and genes you need to design your cell line in-house.

CLD performance icon

You transfect cells

You transfect and generate stable cell lines and use our software for data analysis.

CHO cell line request icon

You request producer cells

You request a producer cell line for a biologic or gene therapy.

CLD process development icon

We do cell line development

We do cell line development and process development at our site.

Up to date icon

We share progress

We share progress and data with you using 
our software.

Ship stable cell lines icon

We ship you producer cell banks

We ship you clonal cell banks and transfer the process to your site.

Choose the right system for you

LV Edge Packaging System

Best for: Speed

Lv Edge Packaging System Schematic

We transfer our system to your lab

We ship you our clonal suspension packaging host cell line and grant access to our software, which you use to design and request DNA. You use our system to perform lentiviral production at your facility.

Transient

Packaging

Low cost

Antibody
Antibody

Low manufacturing complexity

Antibody
Antibody

Low supply chain risk

Antibody
Antibody

Scalability

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Antibody

Rapid development timeline

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LV Edge Producer System

Best for: Scale and reproducibility

Lv Edge Producer System Schematic

We perform services in our lab

Using the LV Edge Producer System, we perform fully-stable cell line development and bioreactor process development, transferring them to your facility for lentiviral production.

Transient

Producer

Low cost

Antibody
AntibodyAntibody

Low manufacturing complexity

Antibody
AntibodyAntibody

Low supply chain risk

Antibody
AntibodyAntibody

Scalability

Antibody
Antibody

Rapid development timeline

Antibody
Antibody
Cell line delivery

We provide tools for you to develop a cell line

We will ship the software, cells, and genes you need to design your cell line in-house.

Plasmid design interface

You design DNA

You use our software to design and optimize genetic constructs using best-in-class parts and models.

Ship DNA icon

We build DNA

We will ship the software, cells, and genes you need to design your cell line in-house.

DNA transfection into cells

You transfect cells

You transfect and generate stable cell lines and use our software for data analysis.

Cell line selection

You request producer cells

You request a producer cell line for a biologic or gene therapy.

DNA design and development interface

We do cell line development

We do cell line development and process development at our site.

Communication bubbles

We share progress

We share progress and data with you using 
our software.

Cell line delivery

We ship you producer cell banks

We ship you clonal cell banks and transfer the process to your site.

LV Edge Packaging System

Best for: Speed

We develop a cell line for you

Using our platform, we will design a custom cell line specifically for your needs and ship it to you.

LV Edge Packaging System Overview

We transfer our system to your lab

We ship you our host cells and grant access to our software, which you use to design and request DNA. You use our system to perform lentivirus manufacture at your facility.

Transient

Packaging

Low cost

Antibody
Antibody

Low manufacturing complexity

Antibody
Antibody

Low supply chain risk

Antibody
Antibody

Scalability

Antibody
Antibody

Rapid development timeline

Antibody
Antibody
CHO cell line request icon

You request producer cells

You request a producer cell line for a biologic or gene therapy.

CLD process development icon

We do cell line development

We do cell line development and process development at our site.

CLD process development icon

We share progress

We share progress and data with you using 
our software.

Up to date icon

We ship you producer cell banks

We ship you clonal cell banks and transfer theprocess to your site.

LV Edge Producer System

Best for: Scale and reproducibility

Ship CHO cells icon

We provide tools for you to develop a cell line

We will ship the software, cells, and genes you need to design your cell line in-house.

DNA design icon

You design DNA

You use our software to design and optimize genetic constructs using best-in-class parts and models.

Ship DNA icon

We build DNA

We will ship the software, cells, and genes you need to design your cell line in-house.

CLD performance icon

You transfect cells

You transfect and generate stable cell lines and use our software for data analysis.

LV Edge Producer System Overview

We perform services in our lab

Using the LV Edge Producer System, we develop a stable cell line containing your gene of interest and ship it to you to perform lentivirus manufacture at your facility.

Transient

Producer

Low cost

Antibody
AntibodyAntibody

Low manufacturing complexity

Antibody
AntibodyAntibody

Low supply chain risk

Antibody
AntibodyAntibody

Scalability

Antibody
Antibody

Rapid development timeline

Antibody
Antibody
Contact us

Speak to a member of our team

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CONTACT US

We're hiring at the intersection of biology, engineering, and machine learning.

Asimov team at their Boston office
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