RNA Edge System

Optimizing expression of RNA therapies. Go from sequence to validated candidates in a matter of weeks.

ACCELERATING RNA THERAPEUTICS

A lab-in-the-loop platform for AI optimization of RNA therapeutic candidates

Applications

Expression profile is a primary determinant of therapeutic success, but most RNA sequences are still optimized using outdated single-variable approaches, leaving significant performance potential unrealized. Achieving high expression and durability requires balancing multiple interdependent factors simultaneously: translation dynamics, RNA secondary structure, and genetic element interactions.

RNA Edge was built to solve this multi-dimensional design problem. It's a fully integrated system for optimization of expression profile, with every design validated in application-relevant cell types.

We deliver high-confidence RNA designs in weeks.

Benefits of RNA Edge

Antibody

End-to-end RNA optimization

  • AI sequence optimization, novel genetic parts, and experimental validation to improve expression profile.
Virus

Broad therapeutic applicability

  • Supports linear mRNA and circular RNA across cell therapy, genome editing, and vaccines.
Strand of DNA

Proven performance

  • Validated in large biopharma programs for CAR and Cas9.

System performance

Data-driven computational and synthetic biology, validated in the lab.

RNA Edge combines proprietary computational models and high-performance genetic parts with integrated screening to deliver validated improvements across the variables that determine therapeutic success.

From sequence to delivery of top candidates

RNA Edge takes your program from sequence design through wet lab validation in weeks, delivering high confidence, data-backed candidates.

Contact us

Ready to optimize your RNA 
therapeutic?

Country
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form
CONTACT US

We're hiring at the intersection of biology, engineering, and machine learning.

Asimov team at their Boston office
Illustration of a white blood cell