CHO Edge Expression System
Integrating genetic tools and data-driven models to routinely achieve titers of 6–10 g/L across modalities
Reduce the risk of a low titer cell line
Expression can vary significantly between different molecules using the same vector. Asimov’s CHO Edge System incorporates a GS knock-out CHO host, a hyperactive transposase, a library of >2500 characterized genetic elements and advanced computational tools, enabling exploration of vector design space.
System performance
Two ways to work with us
We transfer the CHO Edge System to your lab
We ship you CHO cells and grant software access
Vials of GMP-banked CHO cells with regulatory documentation are shipped to you, and your team is onboarded into our vector design software.
You design DNA
Using our parts and computational models, you design a set of expression vectors. We're here to help if needed.
We ship your DNA
We construct, prepare, sequence, QC, and ship plasmid DNA direct to your facility.
You perform cell line development
You transfect and generate stable cell lines, with technical support from our team.
We perform CLD services in our lab
You request a stable CHO cell line
Your cell line development campaign begins with you providing us with an amino acid sequence.
We perform cell line and upstream
process development with CHO Edge
CLD and PD is all done at our site using state-of-the-art equipment and industry-leading timelines.
We keep you up to date at every stage
We’ll collaborate and share the latest data, to ensure project success.
We ship you clonal, stable cell lines
Vials of research cell banks are shipped to your lab, the process is transferred to your site, and documentation for your regulatory filing supplied.
We provide tools for you to develop a cell line
We will ship the software, cells, and genes you need to design your cell line in-house.
You design DNA
You use our software to design and optimize genetic constructs using best-in-class parts and models.
We build DNA
We will ship the software, cells, and genes you need to design your cell line in-house.
You transfect cells
You transfect and generate stable cell lines and use our software for data analysis.
You request producer cells
You request a producer cell line for a biologic or gene therapy.
We do cell line development
We do cell line development and process development at our site.
We share progress
We share progress and data with you using our software.
We ship you producer cell banks
We ship you clonal cell banks and transfer the process to your site.
We transfer the CHO Edge System to your lab
We develop a cell line for you
Using our platform, we will design a custom cell line specifically for your needs and ship it to you.
We ship you host cells and grant software access
Vials of GMP-banked host cells with regulatory documentation are shipped to you, and your team onboarded into our CAD software.
You design DNA
Using our parts and computational models, you design and optimize expression vectors.
We ship your DNA
We construct, prepare, sequence, QC, and ship plasmid DNA direct to your facility.
You perform cell line development
You transfect and generate stable cell lines, with technical support from our team.
You request producer cells
You request a producer cell line for a biologic or gene therapy.
We do cell line development
We do cell line development and process development at our site.
We share progress
We share progress and data with you using our software.
We ship you producer cell banks
We ship you clonal cell banks and transfer theprocess to your site.
We perform cell line development services in our lab
You request a stable cell line
Your cell line development campaign begins with you providing us with an amino acid sequence.
We perform cell line and upstream process development
CLD and PD is all done at our site using state-of-the-art equipment and industry-leading timelines.
We collaborate and keep you up to date
At every stage, we’ll collaborate and share the latest data, to ensure project success.
We ship you clonal, stable cell lines
Vials of clonal cell banks are shipped to your lab, and the process is transferred to your site, as well as documentation for your regulatory filing.
